Outraged that he's being forced to work with his university nemesis, Barry Kripke (guest star JOHN ROSS BOWIE), Sheldon faces a crisis of conscience.
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When Sheldon and Leonard fight, it affects Penny and Amy's living arrangements. Meanwhile, Raj takes care of Mrs. Wolowitz while Howard is away.
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Leonard, Sheldon and Howard try to advance the cause of women in science by speaking with junior high girls about their future careers, while Raj plans his date with Lucy.
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To open or not to open? When Howard finds a letter from his father, he's forced to confront his past. And Leonard and Penny throw a grown-up cocktail party at the apartment.
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After one of his favorite TV shows gets canceled too soon, Sheldon feels lost, so Amy tries to help him get over his compulsive need for closure by retraining his brain.
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Leonard and Sheldon hire Professor Proton (guest star BOB NEWHART), the host of their favorite childhood TV show to perform. Raj leaves his dog with Howard and Bernadette.
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When the girls' trip to Vegas falls through, the guys invite them to a Dungeons & Dragons date night that causes Sheldon and Amy's relationship to take an unexpected turn.
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Leonard is away at sea, so Sheldon & Penny spend some time together and spill some revealing secrets. Meanwhile, Howard comes to Raj's aid after his breakup with his girlfriend.
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Leonard returns from the North Sea expedition and finds things chilly between him and Sheldon, while Howard's relationship with his mother opens the door to questions about his masculinity.
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Sheldon is fit to be tied when Amy ruins one of his favorite adventure films, while Leonard finds the key to getting Penny to do his bidding, and Raj & Stuart get creative with their online-dating profiles.
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